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During seizures, elevated levels of glutamate can lead to overstimulation of glutamate receptors, particularly N-methyl-D-aspartate (NMDA) receptors (Vasilev et al., 2018)

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Preclinical studies have indicated that these compounds markedly improve intervertebral disc structure and suppress inflammatory responses in animal models of IDD, highlighting their potential clinical applications (47,88)

Cai Y, Wang Z, Liu X, Wei L, Li S, Zheng X, Xu X

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