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With millions of Americans already taking GLP-1 medications and use continuing to grow, these effects on preventing and treating substance use disorders could have significant impact at the population level

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The mechanism aligns with decades of research on weight loss and reproductive health: a 2019 study in *Obesity* demonstrated that even modest weight loss (510%) can shift estrogen metabolism and cycle regularity

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Do you know how much fun we have together no matter where we go?' Khloe says