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These models should integrate key features such as vascular remodeling, BBB integrity, and neuronal-vascular cell interactions to accurately simulate neurovascular dynamics

Known as the "master antioxidant," glutathione is essential for combating oxidative stress and supporting detoxification

This modification, a subtype of S-thiolation, involves the formation of mixed disulfide bonds between glutathione and the cysteine residues of target proteins

Although it has been argued that clinically relevant doses of APAP should be used in such studies, it is expected that recapitulating conditions in susceptible humans using healthy laboratory animals will require higher drug doses than those commonly encountered by humans (Fig

Pay attention to how you feel over the course of 30 to 60 days

lycopersicum reference genome (SL4.0) and gene annotation (ITAG4.1) using STAR v2.7.9a 35 and transcripts per million (TPM) values were calculated using RSEM (v1.3.1) 36