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doi: 10.3389/fmed.2025.1580645 Received 21 February 2025 Accepted 09 May 2025 Published 02 June 2025 Volume 12 - 2025 Edited by Piergiorgio Messa, University of Milan, Italy Reviewed by Jack D

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Conclusion PLB ameliorates DHT-induced mitochondrial dysfunction and ferroptosis in KGN cells by inhibiting YTHDF1 expression, and its action is dependent on the mechanism by which YTHDF1 regulates SLC7A5 translation through m6A modification