Subsequently, based on individual glycemic response and tolerability, the dose can be increased in 2.5 mg increments every four weeks up to 15 mg per week
Originally developed for managing type 2 diabetes, these medications are now being explored as potential solutions for weight and metabolic issues in women with PCOS (Polycystic Ovary Syndrome)
However, these drugs are very expensive, have not been shown to prevent colectomy in severe ulcerative colitis (Aratari 2008), and may cause autoimmune diseases, cancer, infections, and viral reactivation syndromes including shingles (Colombel 2004)
(PubMed) Carr AC, Rosengrave PC, Bayer S, Chambers S, Mehrtens J, Shaw GM
Research on the effect of GLP-1RAs on cardiovascular outcomes in patients with advanced DKD (eGFR 50%, progression to ESKD with dialysis, and cardiovascular death
108,109,110 The lack of efficient repair of these damaged tissues is the consequence of stem cell decline and aging