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Using equipment outside its calibrated working range

Figure 1 depicts the action of GLP-1 RAs on target tissues

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Previous studies showed that several PAMs of GLP-1R, such as the most characterized electrophilic chemotype compound BETP 23,24 and the substituted quinoxaline compound 2 (6,7-dichloro-3-methanesulfonyl-2-tert-butylamino-quinoxaline) 25,26 , were able to initiate or promote receptor activation 9,27

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