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While the risk of kidney injury risk is rare, it is often linked to dehydration from digestive side effects of the drug such as nausea and vomiting
GLP-1 (glucagon-like peptide-1) is a hormone released in the gastrointestinal tract in response to food consumption
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In addition, they allow the space-time control to release PROTAC at the intended site of action, which significantly enhances the therapeutic effect [36,37,38,39,40]
But topical application has inherent limitations