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Melasma also has a high rate of recurrence, despite effective therapies like hydroquinone or triple combination cream (hydroquinone 5%, hydrocortisone 1%, and tretinoin 0.1%)

However, the authors emphasize that it is difficult to determine precisely what proportion of the effect results from direct anti-inflammatory action and what proportion results from weight reduction and improved metabolic control

This commitment to a healthier lifestyle will help maximize the benefits of Semaglutide GLP-1 and ensure long-term success in managing both weight and metabolic health

Neurosci Biobehav Rev 25:235-260

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