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Furthermore, evidence from multi-omics studies (Huang et al., 2023), Mendelian randomization analyses (Lei et al., 2023

Proteomic identification of nitrated brain proteins in traumatic brain-injured rats treated postinjury with gamma-glutamylcysteine ethyl ester: insights into the role of elevation of glutathione as a potential therapeutic strategy for traumatic brain injury

The IGF-1/AKT/PKM2 axis not only controls energy metabolism but it can regulate gene expression and tissue homeostasis through STAT3 signaling

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NAC acts as a mediator of glutathione production and protects cells from damage

(33896531) However, the added benefit of this additional dose is unclear