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It says GLP-1 drugs alone are not appropriate primary treatment in that situation, and that a person should work with an endocrinologist to address the underlying cause
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10.1007/s11033-022-07673-x 67 MehtaV.SumanP.ChanderH
A realistic expectation of energy changes, combined with proactive monitoring, significantly improves treatment adherence and outcomes
Phase III results for retatrutide are set to be released later in 2025 and in early 2026, but an earlier phase II trial recorded between a 7.2% and 17.5% reduction in body weight after 24 weeks, depending on the dose (7.2% on 1mg, 17.5% on 12mg), and up to a 24.2% reduction in body weight after 48 weeks for those on 12mg (-8.7% change for those on 1mg) 8
There are several GLP-1 receptor agonists available, each with its own formulation and dosing schedule
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