Main body Anthracyclines, particularly doxorubicin, have emerged as crucial components in cancer treatment, demonstrating significant antitumor activity across various malignancies
iPLA2-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4
Updated for 2026 with recent enforcement actions, OECD IT security guidance, and New Approach Methodologies (NAMs) ICH Q10 Guide: Implementing a Pharmaceutical Quality System An in-depth guide to ICH Q10 Pharmaceutical Quality Systems (PQS), updated for 2026 with ICH Q9(R1), Q12-Q14 developments, FDA QMM program updates, and AI-driven quality management trends.
Identification of TMAO-producer phenotype and hostdietgut dysbiosis by carnitine challenge test in human and germ-free mice
Such a significant reduction in mass is particularly beneficial for females during this life phase, who often face weight gain due to hormonal fluctuations
After 90 minutes, the suture was withdrawn, and successful reperfusion was confirmed by rCBF restitution to 90120% of baseline within 10 minutes