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Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

Pro-inflammatory mediators are secreted which give rise to a phenomenon known as senescence-associated secretory phenotype (SASP) 11,12

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226,227 Stress-related diseases, neural protection, neurological inflammation, and neurogenesis are all affected by the PYY, which may activate Y4 receptors and then engage in anxiety and depression regulation

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Additionally, a positive regulatory relationship between LPS-induced macrophage activity and ferroptosis sensitivity has been observed