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Similarly, during the dose escalation phase of tirzepatide therapy, when gastrointestinal adverse effects are most common, temporary alcohol avoidance may be prudent until tolerance is established at the maintenance dose

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Gastrointestinal symptoms: Some peptides, especially GLP-1 receptor agonists such as semaglutide or tirzepatide, can slow digestion, which may lead to nausea, vomiting, diarrhea, or constipation

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Astrocytes as Neuroimmunocytes in Alzheimers Disease: A Biochemical Tool in the Neuron-Glia Crosstalk along the Pathogenetic Pathways