Acknowledgements This work was supported by grants from the National multidisciplinary collaborative diagnosis and treatment capacity building project for major diseases (TJZ202104), the Natural Science Foundation of China (82270643, 82070644, 82170621 and 82370645), the Science and Technology Major Program of Sichuan Province (2022ZDZX0019), the Sichuan Science and Technology Program (2024NSFSC0645), 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University (ZYJC18008, ZYGD22006)
Disruption of GSH dynamics typically impairs redox buffering capacity, often manifested as reduced mitochondrial GSH (mtGSH) levels
The NICE guidelines on obesity management do not include B12 supplementation as a therapeutic option for weight reduction in the absence of documented deficiency
alpha-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults
Slower titration improves tolerability at the cost of delayed maximum efficacy
Such method overcomes the expense and/or inconvenience of intravenous glutathione administration and also overcomes the increased likelihood of side-effects associated with the ingestion of high doses of glutathione