Barriers to insulin injection therapy: Patient and health care provider perspectives
Pricing starts at $600 for (4) once-weekly shots and coaching sessions
The practical goal is to reduce avoidable contributors: titrate thoughtfully rather than racing to the highest dose, avoid unnecessarily rapid weight loss, prioritize adequate protein, perform resistance training to preserve lean tissue, and monitor for iron, zinc, vitamin D, vitamin B12, vitamin A, and other deficiencies when intake is substantially reduced
Lu SC, Chen M, Atangan L, et al
[3] Subsequently, activation of secondary pathways, including protein kinase A (PKA) and Epac2, alters cell ion channel activity, causing elevated levels of cytosolic Ca 2+ that enhance exocytosis of insulin-containing granules
PMID 23523778