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[DOI] [PubMed] [Google Scholar] 323

They carry a boxed warning for people with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

Gastric sleeve surgery (also known as sleeve gastrectomy or vertical sleeve gastrectomy): A surgeon removes about 80 percent of the stomach, leaving behind a sleeve or tube made up of the remaining 20 percent

and are used with permission

Instead, it is a preclinical synthetic small molecule that activates estrogen-related receptors and has produced exercise-associated metabolic effects in cells and animal models