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Mateus, F., Moreira, S., Martins, A., Oliveira, P., Alves, M., & Pereira, M

[1] [2] Dose reduction or temporary treatment interruption may be necessary for intolerable side effects, with subsequent slower retitration

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Patients had a mean age of 57 years and 53% were men

Tirzepatide is a dual GLP-1RA and glucose-dependent insulinotropic polypeptide receptor agonist, exerting synergistic effects on insulin secretion and weight reduction [4], and offering enhanced efficacy compared to semaglutide