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Brain 2005, 128: 17471763

The expression of immune checkpoint molecules, PD-L1 and indoleamine 2, 3-dioxygenase1 (IDO1), is responsible for this process (121)

Glutathione protects mitochondrial function and maintains cellular energy balance

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Like semaglutide, tirzepatide enhances insulin sensitivity and suppresses appetitebut adds the GIP pathway for potentially even more profound effects