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Some studies, however, have reported decreased salty taste perception in individuals with higher BMI (133, 134)

However, some people who have conscious sedation fall asleep during the procedure

In Eli Lilly's pivotal Phase 3 ATTAIN clinical trialsthe studies that led to FDA approvalparticipants taking orforglipron achieved average body weight reductions of approximately 7.9% to 8.7% over 36 to 40 weeks, depending on the dosing

Suppresses appetite (central action): Reduces hunger signals in the brain, leading to decreased food intake and weight loss 1,2

Before stopping or reducing treatment, patients should discuss a maintenance strategy with their physician