In a Phase 2b study in people with type 2 diabetes and obesity over 54 weeks, treatment with cotadutide at doses of 100-300 g daily improved some non-invasive markers of NAFLD such as transaminase levels, the FIB-4 index, fatty liver disease fibrosis score (NFS) and fatty liver index (FLI) but fatty liver disease was not assessed directly with liver biopsy
The drugs have been on the FDAs drug shortages list since 2022
K7M2-Luciferase (K7M2-Luc) cells are cancer cells that express the reporter gene luciferase, which reacts with its substrate (luciferin) to generate chemiluminescence
Prior to 2021, white patients represented greater than 70 percent of trial participants over at least 5 years in the areas of analgesia/anesthesiology/anti-inflammatory, cardiovascular disease, endocrinology/metabolism/bone, infectious disease (nonviral), oncology, ophthalmology, and pulmonary
Buller R, Peterson ML, Almarsson , Leiserowitz L (2002) Quinoline binding site on malaria pigment crystal: a rational pathway for antimalaria drug design
For operators building or scaling a prescription refill service, the correct question is not what is the hourly rate? but what does unreliable patient support cost us in churn, escalations, and compliance exposure over three years? On that calculation, Helpware CXs operational metrics make a compelling case
