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The GLP-1 receptor agonists used clinically are based on exendin-4 and native GLP-1 and are available as formulations for daily or weekly s.c

In the next article, well dig deeper into the mental health effects of GLP-1 medications

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A very high dose of 30 g shows little difference between males and females

The STEP 1 trial showed semaglutide produced average weight loss of 14.9% of body weight over 68 weeks, compared with 2.4% with placebo

More serious but rare adverse events include pancreatitis, gallbladder events, and hypoglycemia (primarily in patients using insulin simultaneously)