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Its always best to reconstitute and draw a fresh dose from a properly stored vial right before use

It is the delivery vehicle, the preservative system, and the single point of failure in the reconstitution chain

Retrieved March 7, 2012

But a huge number of meat eaters are also deficient and likely dont know it B12 is absorbed through the stomach, and our ability to assimilate it through the stomach wall decreases with age, as well as due to any stomach issues like IBS, Crohns, and Celiac Disease, and medications that impact the stomach like metformin, antacids, PPIs, and ibuprofen

Why Do You Need Methylation