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Frozen: 1 month (avoid repeated freeze/thaw cycles) Methodology Process(es) used to perform the test
The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy
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Finally, we highlight major limitations in the current evidencesuch as heterogeneous dosing regimens, the scarcity of long-term clinical data, and insufficient mechanistic validation under MASLD conditionsand propose directions for future translational research