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Notably, the majority of mechanistic data supporting this concentration-dependent model derives from preclinical studies using mouse pancreatic -cells and clonal cell lines, with limited validation in human islet studies, necessitating further clinical investigation to confirm these concentration thresholds in human diabetes treatment [23,24,25,26]

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Rival Novo Nordisk took a similar approach, pouring $16.5 billion into acquiring Catalents manufacturing sites through its investment arm to boost Wegovy production

Clear is expected for non-B12 formulations

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Or have we reached a point where the fundamental barriers are largely about government priorities, service infrastructure and investment