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A study in mice reported that metformin increases the expression of precursor proteins such as preproglucagon and proglucagon in the large intestine, potentially increasing GLP-1 production and secretion [61]

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Among the enzymes contributing to the balance of the redox system, GSTP1/P2 catalyze the elimination of electrophilic oxidants

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TABLE 1 Literature on MSC therapy for PH in the last decade

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