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Structured follow-ups Monitoring and education to prioritize safety and effectiveness

DIO mice received 45% HFD for at least 12 weeks before the study

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Research protocols should assess renal and hepatic function and consider dose adjustments or enhanced tracking in subjects with impairment

A high-affinity molybdate transporter in eukaryotes

These technologies provide crucial insights into how EEDs affect specific testicular cell populations, including spermatogonial stem cells, Sertoli cells, and Leydig cells, allowing researchers to understand cellular specificity of toxic responses