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Nevertheless, it cannot be excluded that the integrative treatment we administered acted on liver function through an improved expression/synthesis of the hepatic insulin degrading enzyme (IDE), which is responsible of at least 70-80% of the clearance of circulating insulin (38)

The results suggested that GLP-1 agonists use was associated with lower mortality (both all-cause and cardiovascular mortality) compared with DPP-4 inhibitors or placebo or no treatment

AD is characterized by a decade-long prodromal stage, and dementia diagnosis typically occurs in the late biological stage of AD, by which time substantial amounts of A and tau proteins have accumulated in the cortex [101]

Treatment with GSH 0.21.0 mg/mL did not significantly change the proportion of viable cells at 72 h compared to vehicle-treated cells (Figure 2a)