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Gene expression and phosphorylation of AANAT (the rate-limiting enzyme in melatonin synthesis) become downregulated

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FIGURE 2 On the other hand, in addition to its well-known functions, PGC1, a master regulator of mitochondrial biogenesis, positively regulates mitophagy by directly inducing the expression of transcription factor EB (TFEB) that mediates lysosomal biogenesis (Settembre et al., 2011)

Estrogenic effects of silymarin lead to increasing the uterine weight and endometrial height, in addition to hypertrophy of luminal epithelium

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The microbiome-mitochondrion connection: common ancestries, common mechanisms, common goals