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Under normal physiological conditions, Nrf2 is bound to Kelch-like ECH-associated protein 1 (Keap1), and is primarily located in the cytoplasm

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Any disruption in mitochondrial ATP production can impede the livers detoxification capabilities, disrupt the synthesis of essential molecules, and affect ionic balance

The patient should be apprised of the potential hazard to the embryo or fetus, and increased fetal monitoring might be warranted if exposure occurred