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However, MM is still incurable for the majority of patients who become refractory to treatment and ultimately relapse, thus further development of new therapeutic agents is warranted, such as specific inhibitors targeting activated oncogenes

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Additional identifiers for cheminformatics and database cross-referencing include PubChem CID 9941957 and InChIKey HEEWEZGQMLZMFE-RKGINYAYSA-N

In contrast, the results of qRT-PCR revealed that the expression levels of key genes ( BECN1 , ATG3 , ATG4D , ATG5 , ATG12 , and SQSTM1 ) of the autophagy signal transduction pathway in HuOCSCs overexpressing ATF4 and treated with anisomycin were significantly higher than those in the control group (Figure 6B)

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