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Clinical questions A 50-year-old woman with a long-term history of severe facial eczema presents with nonpruritic facial erythema and scattered papules on the cheeks and forehead with no crusting, scaling, indentation, or comedones

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Copper-ATSM as a treatment for ALS: support from mutant SOD1 models and beyond

Collectively, these recent contributions argue that future GSH-centric redox sensing and nanomedical approaches should (i) incorporate organelle targeting (especially mitochondria) to exploit subcellular redox heterogeneity, (ii) embed analyte-responsive activation into both therapeutic and imaging components, (iii) combine biochemical sensing with optical or thermal engineering for spatiotemporal control, and (iv) favor clinically translatable carriers (e.g., PLGA) for delivery