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Sirtuins are a family of NAD-dependent deacetylases that remove acetyl groups from proteins, influencing gene expression, DNA repair, metabolism, and stress responses

Acknowledgements The authors thank the Cloning, Cell Expression, Protein Purification and Assay Development Core Facilities of iHuman Institute for their support

from the ingestion of contaminated food products, such as rice

6 Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

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