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In the cardiac magnetic resonance (CMR) sub-study of the SUMMIT trial, in comparison with the placebo, the treatment of obesity-related HFpEF with tirzepatide can lead to a reduction in LV mass and pericardiac adipose tissue

There are some important drug interactions to consider

Importantly, patients treated with GLP-1 RAs required less acetazolamide, yet showed no worsening of papilledema [27]

This leads to rapid bacterial growth and peptide degradation

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