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However, activation of the afferent branch of the vagus nerve by capsaicin or activation of the vagus nerve and ENS by exendin-4, another GLP-1RA, failed to increase NE concentrations (Fig

The following individuals participated with the task force at various points throughout the consensus development process: Victoria Gomez, Myron Powell, Eric Likar, Angela F

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In chronic pain states, TRPV1 channels are upregulated in nociceptive neurons, which lowers stimulation thresholds and increases pain perception, as reported in hyperalgesia or allodynia 21