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These disturbances ultimately impair testosterone production by LC and compromise the supportive function of SC in spermatogenesis, resulting in impaired spermatogenic function ( 3.3 Advanced glycation end products AGEs can severely impair sperm function through multiple mechanisms

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Neurotoxicant trimethyltin (TMT) induces a significant reduction of cell survival, neuronal differentiation and concomitant earlier activation of cleaved caspase-3

Four weeks is more conservative and preferred when running multiple cycles back to back