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As your body adapts to the medication over 24 weeks, your internal thermostat may reset temporarily, making you feel colder than usual

Its active ingredient, semaglutide, is a GLP-1 (glucagon-like peptide-1) receptor agonist

In mid-life, several things often happen together: people move less and few invest in resistance training upper-body and fast-twitch muscle fibres are lost muscle becomes less responsive to dietary protein protein intake is often inadequate or poorly distributed In the absence of sufficient availability of amino acids and skeletal workload, the body quietly breaks down muscle instead to supply amino acids for tissue repair and immune function

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