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What dosing protocol was used in the landmark FOXO4-DRI mouse study

MMWR Morb Mortal Wkly Rep 66(15):397403 De Filippo C et al (2010) Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

Pfizer subsequently pursued a once-daily modified-release formulation of danuglipron to improve the pharmacokinetic profile and reduce peak-related gastrointestinal side effects