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Of approximately 4,000 affected genes, 59% are upregulated while 41% are downregulated, generally shifting expression patterns from diseased toward healthier states

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These glycaemic fluctuations can influence gut microbiota composition by selectively promoting the growth of glucose-utilizing bacteria while suppressing beneficial fiber-fermenting species

Thus, a better understanding of the interaction of diet, gut microbiota, and disease is needed before dietary recommendations can be made

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