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The real-world results we see in clinic come from combining a GLP-1 medication with structured nutrition advice, regular weighing-in, and a clinician available to manage side effects

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We saw a lower risk associated with semaglutide compared to other medications, but we dont know exactly the mechanism yet, said Rong Xu, the author of the study and a professor of biomedical informatics at Case Western Reserve University

Briefly, a significant drug main effect ( p = 0.001), as well as a significant drug time-point interaction effect ( p = 0.01), was shown for insulin, suggesting that cannabis administration blunted the increase in blood insulin concentration observed under the placebo condition (Fig