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The Rg stays very constant in the whole simulation for both inhibitors with slight changes in Rg of N3 (Fig

Discussion At present, clinical remedy of patients with chronic hepatitis B is mainly on the foundation of regular antiviral treatment, which can improve the patients liver function to a certain extent, turn HBV-DNA negative, delay the process of liver fibrosis, and has a definite impact on ameliorating the patients quality of life and survival rate

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