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Obesity Obesity, affecting over 650 million people globally, significantly contributes to morbidity and mortality [11]

It is worth noting that this cardioprotective effect of exenatide outweighed the fact that a greater proportion of patients on exenatide treatment possessed CVD risk factors such as prior ischemic heart disease, obesity, hyperlipidemia, and hypertension [98]

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Arch Biochem Biophys 429(2):123133 Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K et al (1999) Distinct roles of thioredoxin in the cytoplasm and in the nucleus a two-step mechanism of redox regulation of transcription factor NF-B

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