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A possible (additional) reason for improvement could be the low intake of proteins (8% in this study) which increases the bioavailability of levodopa, a drug used to treat motor symptoms

Both can produce skin improvements but through different primary mechanisms

"Peptide math is not difficult because the underlying formula is advanced," said a spokesperson for the PeptidesCalculator team

While it is better studied in skin and wound healing contexts, there is emerging preclinical data suggesting GHK-Cu supports extracellular matrix remodeling and anti-inflammatory gene expression in gut tissue

doi: 10.1016/j.jinorgbio.2008.11.007

It may be related to the increase of oxidative damage, so the amount of GSH is a vital factor to measure the body's antioxidant ability