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doi: 10.1007/s12011-022-03217-3 4

Conversely, macrophages similar to M2 enhance tumor blood vessel formation, immune suppression, cancer cell infiltration, and spread by emitting anti-inflammatory agents such as TGF-, PGE2, and VEGF [61]

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BPC-157, known for modulating cytokine levels and inhibiting inflammatory enzymes, may work synergistically with Osthole and 5a-hydroxy laxogenin to reduce pro-inflammatory mediators