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However, this pathway is reported to be inactive in most tissues, and in the few tissues in which it is active, its function is reduced in tumours from the corresponding tissue 16

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

PMID 31308748

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Subjects who received GPLC were also noted as having lower levels of malondialdehyde, a lipid peroxidation biomarker indicating free radical mediated oxidation of lipids