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W., Burmeister, M
Risk of bone fractures associated with glucagon-like peptide-1 receptor agonists' treatment: a meta-analysis of randomized controlled trials
Alcohol consumption deserves special attention
Reconstitute with bacteriostatic water for research handling
SURMOUNT-3 and SURMOUNT-4 Trials (2023) In a 2023 NEJM publication , researchers reported that Retatrutide: Produced an average of 24.2% total body weight loss at 48 weeks in individuals without diabetes Patients on the highest dose lost over 58 pounds on average Outperformed all currently available GLP-1 and GIP analogs Additional findings included: Significant reduction in liver fat (up to 85%) Improved insulin sensitivity and HOMA-IR scores Reduced blood pressure, triglycerides, and inflammation markers These results are unmatched in obesity pharmacotherapy history and suggest that Retatrutide could soon set a new gold standard for metabolic treatment
While many folks do well with compounded versions, they are not FDA approved and may vary in consistency
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