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The cysteine residue carries a sulfur-containing thiol group, and that thiol is the chemical engine behind nearly everything glutathione does

Nat Commun 11:3894 Fan X, Wang T, Han M, Gu Y, Sun G, Peng X, Shou Q, Song H, Liu W et al (2022) Dual CEA/CD44 targeting to colorectal cancer cells using nanobody-conjugated hyaluronic acid-modified mesoporous silica nanoparticles with pH-and redox-sensitivity

Acta 1001 , 102106 (1989)

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Taken together, multimodal synergistic therapy on the basis of nanotechnology does provide revolutionized value and practical application in cancer therapy

This requires NADPH, making mitochondrial and cellular energy metabolism relevant to antioxidant resilience