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The robust weight loss combined with a well-tolerated safety profile reinforces our confidence in the clinical development programme [of CT-388] as we advance to phase III trials" Dr Levi Garraway, PhD, Roches Chief Medical Officer and Head of Global Product Development, said: We are pleased to see such meaningful weight loss in people treated with CT-388

These agents bind to GLP-1 receptors expressed throughout the body, including pancreatic beta cells, the gastrointestinal tract, and central nervous system regions involved in appetite regulation

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Muscle strength relative to body weight increased with the three active treatments compared with placebo (Fig

Material preparation, data collection and analysis were performed by Ying Xiong, Te Liu, Juan Chen

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