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GIP Receptor Activity The glucose-dependent insulinotropic polypeptide receptor influences insulin release in response to nutrient intake and modulates how adipose tissue handles energy substrate

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49 Treatment with liraglutide 0.9 mg daily and 1.2 mg daily after 96 weeks and six months, respectively, both demonstrated reductions in hepatic steatosis, and the 0.9 mg treatment group underwent histological assessment revealing improvement in hepatitis

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At 68 weeks, treatment was stopped but a small group continued taking semaglutide for a year as part of an extension trial

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