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In December 2017, glycopyrrolate (GLY) inhalation solution (Lonhala [Sunovion Pharmaceuticals, Inc., Marlborough, MA, USA]) 25 g twice daily (BID) delivered via the eFlow Closed System (CS) Nebulizer (Magnair [PARI Pharma GmbH, Starnberg, Germany]) was approved by the US Food and Drug Administration (FDA) for the long-term maintenance treatment of airflow obstruction in patients with moderate-to-very-severe COPD (referred henceforth as nebulized GLY) 6

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