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10.1097/MED.0b013e32835bc703 16

matched for mean body weight at the start of treatment at 770 g 10 g) received daily IP injections of vehicle (1 mL/kg), sCT (3 g/kg), liraglutide (50 g/kg), a combination of sCT and liraglutide (3 g/kg + 50 g/kg) or a stepwise administration of the amylin and GLP-1R analogs, where rats received sCT treatment for the first week, liraglutide treatment for the second week, followed by a combination treatment of sCT and liraglutide for the remaining testing period

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Mean percentage change in body weight ranged from 8.7% with 1 mg to 24.2% with 12 mg, compared with 2.1% for placebo